Chemical, toxicological and environmental aspects of parabens and its substitutes in the cosmetic industry

  • Ingrid Ferreira Costa Departamento de Ciências Farmacêuticas Universidade Federal de São Paulo - Campus Diadema Rua São Nicolau, 210, 2° andar, Bairro Centro CEP: 09913-030, Diadema - São Paulo, Brasil Fone: 55 (11) 4044-0500 Ramal 357
  • Rogério Aparecido Machado Escola de Engenharia Mackenzie, Universidade Presbiteriana Mackenzie, 01302-907, São Paulo, SP , Brasil.
  • Marcio Adriano Andreo Departamento de Ciências Farmacêuticas Universidade Federal de São Paulo - Campus Diadema Rua São Nicolau, 210, 2° andar, Bairro Centro CEP: 09913-030, Diadema - São Paulo, Brasil Fone: 55 (11) 4044-0500 Ramal 357

Abstract

As a result of their effectiveness in low concentrations, low cost of synthesizing and not causing alteration in the organoleptic characteristics of the products, parabens are widely used as a preservative in cosmetics. According to studies, these esters have the potential to interfere with the performance of the endocrine system causing changes in hormones activity, as well as represent a hazard to the environment. This study aimed to evaluate the main chemical, toxicological and environmental aspects of parabens in the cosmetic industry comparing to other preservatives, discussing also the use of plant extracts and essential oils as natural preservatives.

Author Biographies

Ingrid Ferreira Costa, Departamento de Ciências Farmacêuticas Universidade Federal de São Paulo - Campus Diadema Rua São Nicolau, 210, 2° andar, Bairro Centro CEP: 09913-030, Diadema - São Paulo, Brasil Fone: 55 (11) 4044-0500 Ramal 357
Possui graduação em Bacharel em Química com Atribuições Tecnológicas pela Faculdade São Bernardo do Campo (FASB) e Mestranda em Ciências Farmacêuticas pela Universidade Federal de São Paulo (UNIFESP).
Rogério Aparecido Machado, Escola de Engenharia Mackenzie, Universidade Presbiteriana Mackenzie, 01302-907, São Paulo, SP , Brasil.
Possui graduação em Bacharel em Química com atribuições tecnológicas - (1987), latu sensu em Qualidade na área de Engenharia (1991), mestrado em Saneamento Ambiental pela Universidade Presbiteriana Mackenzie (1999) e doutorado em Saúde Pública pela Universidade de São Paulo (2003).
Marcio Adriano Andreo, Departamento de Ciências Farmacêuticas Universidade Federal de São Paulo - Campus Diadema Rua São Nicolau, 210, 2° andar, Bairro Centro CEP: 09913-030, Diadema - São Paulo, Brasil Fone: 55 (11) 4044-0500 Ramal 357
Graduado em Farmacia e Bioquímica pela Universidade Estadual Paulista Júlio de Mesquita Filho (2002), Mestre em Ciências Farmacêuticas pela UNESP (2003), Doutor em Química pelo IQ-UNESP (2008) e Pós-Doutorado pela FCFRP-USP (2010).

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Published
2019-06-29
How to Cite
Ferreira Costa, I., Aparecido Machado, R., & Adriano Andreo, M. (2019). Chemical, toxicological and environmental aspects of parabens and its substitutes in the cosmetic industry, 12(2), 22. https://doi.org/10.22280/revintervol12ed2.435